Depth Chart
| Offense | |||
| Position | |||
| Left Tackle | Jedrick Wills Jr. | Kendall Lamm | |
| Left Guard | Joel Bitonio | Nick Harris | |
| Center | JC Tretter | Evan Brown | |
| Right Guard | Wyatt Teller | Chris Hubbard | |
| Right Tackle | Jack Conklin | ||
| Wide Receiver | Jarvis Landry | Rashard Higgins | Donovan Peoples-Jones |
| Wide Receiver | Odell Beckham Jr. | JoJo Natson | KhaDarel Hodge |
| Running Back | Nick Chubb | Kareem Hunt | D'Ernest Johnson |
| Tight End | Austin Hooper | Harrison Bryant | Stephen Carlson |
| Quarterback | Baker Mayfield | Case Keenum | |
| Defense | |||
| Position | |||
| Left Defensive End | Myles Garrett | Porter Gustin | Adrian Clayborn |
| Left Defensive Tackle | Larry Ogunjobi | Vincent Taylor | |
| Right Defensive Tackle | Sheldon Richardson | Jordan Elliott | |
| Right Defensive End | Olivier Vernon | Joe Jackson | |
| Strong Linebacker | Sione Takitaki | Montrel Meander | |
| Middle Linebacker | B.J. Goodson | Tae Davis | |
| Weak Linebacker | Mack Wilson | Jacob Phillips | Malcolm Smith |
| Left Cornerback | Denzel Ward | Kevin Johnson | M.J. Stewart |
| Right Cornerback | Terrance Mitchell | Greedy Williams | Tavierre Thomas |
| Strong Safety | Karl Joseph | Ronnie Harrison Jr. | |
| Free Safety | Andrew Sendejo | Sheldrick Redwine | |
| Special Teams | |||
| Position | |||
| Kicker | Cody Parkey | ||
| Kick-Offs | Cody Parkey | ||
| Punter | Jamie Gillan | ||
| Kick Returner | Tavierre Thomas | JoJo Natson | |
| Punt Returner | Jarvis Landry | D'Ernest Johnson | Donovan Peoples-Jones |
| Holder | Jamie Gillan | ||
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